Description

Research Associate II, Protein Crystallization 

This position will support the research project team with protein structure information. The Protein Crystallization Researcher will be responsible for processing of soluble proteins and GPCRs, and operate the crystallization facility, supporting multiple ongoing discovery programs.

Good things are happening at Omeros!
 
Come join our Omeros Discovery Team!

Who is Omeros? 
 
Omeros is an innovative biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, immunologic diseases (e.g., complement-mediated diseases) and cancers. Omeros’ lead MASP-2 inhibitor narsoplimab targets the lectin pathway of complement and is the subject of a biologics license application pending before FDA for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy. Narsoplimab is also in multiple late-stage clinical development programs focused on other complement-mediated disorders, including IgA nephropathy, atypical hemolytic uremic syndrome and COVID-19. OMS906, Omeros’ inhibitor of MASP-3, the key activator of the alternative pathway of complement, is in a Phase 1 clinical trial. For more information about Omeros and its programs, visit www.omeros.com.

Requirements

What are your responsibilities?

• Prepare protein crystals for structural analysis
• Setup, inspect and harvest protein crystals for X-ray diffraction analysis
• Manage wet lab equipment for new formulation generation, liquid dispensation as well as crystal inspection and handling
• Operate laboratory robotics for preparing and inspection of crystallization trials
• Manage and document protein crystallization trials data
• Present scientific results effectively
• Attend project meetings

Education, Experience, Knowledge, & Skills Required:

• A BS degree with a minimum of 2 years of relevant experience in protein crystallization is required
• Experience with protein crystallization techniques, especially membrane proteins and/or automated liquid handling or imaging systems is a plus
• Experience in the following areas is not a requirement but a big plus:
  • Coordinating structure determination and protein production efforts with supportive outside research organizations (collaborators, CROs)
  • Supporting the identification of new therapeutics by compound docking, exploring structure activity relationships and fragment screening campaigns
• Demonstrated ability to present scientific results to project teams and management
• Excellent interpersonal, written and verbal communication skills
• Time management skills
• Problem-solving skills

Behavioral Competencies Required:  

• Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates
• Demonstrated ability to work in a team oriented, highly motivated environment including the ability to foster collaboration
• Ability to work effectively under high pressure, handling multiple priorities simultaneously

Physical Demands Required:  

• Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.  
• May encounter prolonged periods of sitting or standing  
• This position requires working around hazardous materials

Other Requirements:

• This position may require some work on weekends and holidays

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed above are representative of the knowledge, skills, and/or abilities required.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.  

Compensation and Benefits

 Omeros is proud to offer a competitive total compensation package designed to support the lives of our employees and their families. The wage scale for this position is $78,000 - $87,500 per year.  Salaries will be determined based on knowledge, skills, education and experience relevant to the role.  Employees are offered medical, dental, vision and life insurance and a 401k plan with a company match.  Employees accrue three weeks of vacation and 80 hours of sick time on an annual basis and receive twelve paid holidays throughout the calendar year.  This position is eligible for bonus and stock options. To learn more about Omeros, please visitwww.omeros.com.

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000.